Complement and humoral immunity

Complement receptors CD21 and CD35 in humoral immunity.

The complement system is a family of proteins that is involved in both innate and adaptive immunity. Complement receptors CD21 and CD35, which recognize activated products of C3 and C4, are predominantly expressed on B cells and follicular dendritic cells (FDCs) in the mouse. In this review, we focus on the role of FDC-expressed CD21 and CD35 in humoral immunity. They are the principle receptor...

Evaluating Complement-Mediated Humoral Immunity to P. falciparum Blood Stages

Understanding mechanisms of immunity that protect from malaria is essential for the development of highly effective vaccines. The merozoite form of the parasite, which invades red blood cells, is an important target of protective immunity (Beeson et al., 2016). Biryukov et al. bring to our attention the potential ability of complement factors to enhance P. falciparum merozoite invasion in vitro...

Cellular and Humoral Immunity

The Abstract was presented at the Fourth Herpes Virus Meeting, Cold Spring Harbor, N. Y. Dr. Pollard's present address is Division of Infectious Diseases, University of Texas Medical Branch, Galveston, Texas. Received for publicatiotn 2 October 1979 anid inl revised forimi 14 December 1979. recovery of phytohemagglutinin transformation often preceded recovery of the responses to viral antigens....

Humoral Immunity and Cell-Mediated Immunity

Humoral Immunity and Cell-Mediated Immunity